"Inactive" ingredients in oral medications.

Title"Inactive" ingredients in oral medications.
Publication TypeJournal Article
Year of Publication2019
AuthorsD Reker, SM Blum, C Steiger, KE Anger, JM Sommer, J Fanikos, and G Traverso
JournalScience Translational Medicine
Volume11
Issue483
Date Published03/2019
Abstract

Oral forms of medications contain "inactive" ingredients to enhance their physical properties. Using data analytics, we characterized the abundance and complexity of inactive ingredients in approved medications. A majority of medications contain ingredients that could cause adverse reactions, underscoring the need to maximize the tolerability and safety of medications and their inactive ingredients.

DOI10.1126/scitranslmed.aau6753
Short TitleScience Translational Medicine